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          2. 產品詳情

            c-di-AMP sodium

            如果您對該產品感興趣的話,可以
            產品名稱: c-di-AMP sodium
            產品型號: GOY-Y0735
            產品展商: 谷研
            產品文檔: 無相關文檔
            發布時間:2023-04-11

            簡單介紹

            c-di-AMP sodiumN/A


            c-di-AMP sodium  的詳細介紹

            性能參數

            產品名稱

            c-di-AMP sodium

            規格

            500μg 1mg

            貨號

            GOY-Y0735

             含量

            >98.00%

            CAS

            N/A

            別名

            N/A

             

             

            化學名

            N/A

            分子式

            C20H24N10O12P2.xNa

            分子量

            分子 N/A

            溶解度

            N/A

            儲存條件

            Store at -20°C

            General tips

             

            用途

            僅供科研

            價格

            電詢

            詳細內容

            c-di-AMP (Cyclic diadenylate) sodium signaling is a central factor in many Gram-positive bacteria regulating cell wall synthesis, potassium ion channels, DNA repair, and biofilm formation. c-di-AMP sodium is also essential for cell growth, survival, and virulence of several well-known human pathogenic bacteria including S. aureus, L. monocytogenes, S. pyogenes, and Mycobacterium spp[1].c-di-AMP sodium combines with model antigens, such as OVA or β-Gal, acts as a potent mucosal adjuvant stimulating both humoral and cellular responses[4].

            [1]. Fahmi T, et al. c-di-AMP: An Essential Molecule in the Signaling Pathways that Regulate the Viability and Virulenceof Gram-Positive Bacteria. Genes (Basel). 2017 Aug 7;8(8). [2]. Ning H, et al. Recombinant BCG With Bacterial Signaling Molecule Cyclic di-AMP as Endogenous AdjuvantInduces Elevated Immune Responses After Mycobacterium tuberculosis Infection. Front Immunol. 2019 Jul 3;10:1519. [3]. Ebensen T, et al. The Combination Vaccine Adjuvant System Alum/c-di-AMP Results in Quantitative and QualitativeEnhanced Immune Responses Post Immunization. Front Cell Infect Microbiol. 2019 Feb 19;9:31. [4]. Sanchez MV, et al. Intranasal delivery of influenza rNP adjuvanted with c-di-AMP induces strong humoral and cellularimmune responses and provides protection against virus challenge. PLoS One. 2014 Aug 20;9(8):e104824.

            .

             

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